{"id":4800,"date":"2024-02-07T11:46:34","date_gmt":"2024-02-07T03:46:34","guid":{"rendered":"https:\/\/regask.com\/?p=4800"},"modified":"2024-11-16T02:19:25","modified_gmt":"2024-11-15T18:19:25","slug":"mise-a-jour-de-la-mhr-sur-le-valproate-au-royaume-uni","status":"publish","type":"post","link":"https:\/\/regask.com\/fr\/uk-mhra-valproate-update\/","title":{"rendered":"Risque accru de troubles du d\u00e9veloppement neurologique chez les enfants\u2026"},"content":{"rendered":"<div class=\"ewa-rteLine\">\n<div class=\"ewa-rteLine\">\n<div class=\"ewa-rteLine\">\n<div class=\"ewa-rteLine\">\n<div class=\"ewa-rteLine\">\n<div class=\"ewa-rteLine\">\n<div class=\"ewa-rteLine\">De nouvelles recherches indiquent un risque plus \u00e9lev\u00e9 de troubles du d\u00e9veloppement neurologique chez les enfants lorsque les p\u00e8res ont pris du valproate trois mois avant la conception.<\/div>\n<div><\/div>\n<div class=\"ewa-rteLine\">L&#039;Agence de r\u00e9glementation des m\u00e9dicaments et des produits de sant\u00e9 (MHRA) du Royaume-Uni examine de pr\u00e8s ces r\u00e9sultats, ce qui incite \u00e0 prendre de nouvelles mesures de s\u00e9curit\u00e9.<\/div>\n<div><\/div>\n<div class=\"ewa-rteLine\">Les patients de sexe masculin sous valproate qui pr\u00e9voient fonder une famille dans un d\u00e9lai d\u2019un an doivent consulter des professionnels de la sant\u00e9 pour\u2026<\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\t<div id=\"gap-1130832061\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1130832061 {\n  padding-top: 60px;\n}\n<\/style>\n\t<\/div>\n\t\n\n\t<section class=\"section\" id=\"section_387354192\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-226015432\">\n\n\t<div id=\"col-1441628199\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n\t<section class=\"section\" id=\"section_1413627424\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n\n<div class=\"row\"  id=\"row-1300895166\">\n\n\n\t<div id=\"col-770004741\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n<h2>D\u00e9sol\u00e9, ce contenu premium est r\u00e9serv\u00e9 aux clients RegASK uniquement.<\/h2>\n<p>Vous souhaitez acc\u00e9der \u00e0 l&#039;int\u00e9gralit\u00e9 du contenu de l&#039;alerte ou parcourir toutes les actualit\u00e9s ?\u00a0<\/p>\n<div class=\"row\"  id=\"row-442814396\">\n\n\n\t<div id=\"col-1308942102\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n<a href=\"https:\/\/app.RegASK.com\/#\/\" target=\"_blank\" class=\"button secondary is-outline\" rel=\"noopener\" >\n\t\t<span>Connexion client<\/span>\n\t<\/a>\n\n\n<a href=\"https:\/\/regask.com\/fr\/demander-une-demo\/\" class=\"button secondary lowercase\" style=\"border-radius:5px;\">\n\t\t<span>R\u00e9server une d\u00e9mo<\/span>\n\t<\/a>\n\n\n<a href=\"https:\/\/regask.com\/fr\/more-insights\/\" target=\"_blank\" class=\"button secondary is-outline\" rel=\"noopener\" >\n\t\t<span>Parcourir les actualit\u00e9s<\/span>\n\t<\/a>\n\n\n\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n<\/div>\n\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n<\/div>\n\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1413627424 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n  background-color: rgb(255,255,255);\n}\n<\/style>\n\t<\/section>\n\t\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_387354192 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n  margin-bottom: -100px;\n  background-color: rgb(0, 49, 117);\n}\n<\/style>\n\t<\/section>\n\t\n\t<div id=\"gap-1202189217\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1202189217 {\n  padding-top: 60px;\n}\n<\/style>\n\t<\/div>","protected":false},"excerpt":{"rendered":"<p>New research indicates a higher risk of neurodevelopmental disorders in children when fathers took valproate three months before conception. The Medicine and Healthcare products Regulatory Agency (MHRA) in the UK, is closely examining these findings, prompting new safety measures. Male patients on valproate planning a family within a year should consult healthcare professionals for&#8230;<\/p>","protected":false},"author":39,"featured_media":4788,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[526,35],"tags":[317,56,319,321,323,325,327,329,331],"class_list":["post-4800","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-united-kingdom-regulations","category-pharma-biotech-latest-insights","tag-mhra","tag-premium-news","tag-valproate","tag-neurodevelopmental-disorders","tag-medication-safety","tag-patient-guidance","tag-healthcare-professionals","tag-reproductive-risks","tag-regulatory-actions"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>UK MHRA Valproate Update | RegASK<\/title>\n<meta name=\"description\" content=\"The UK MHRA provides an update on the valproate study. 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