の California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) has initiated a review process for p,pʹ-bisphenol chemicals under Proposition 65. (1) These substances, including bisphenols and their ethers and esters, have been selected for evaluation by the Developmental and Reproductive Toxicant Identification Committee (DARTIC) for potential listing as reproductive toxicants.
OEHHA is currently requesting scientific information to support the development of hazard identification materials. Submissions should include animal studies, human epidemiological data, or evidence on mechanisms of reproductive or developmental toxicity.
Details of the Review Process
OEHHA will compile and prepare hazard identification materials for DARTIC’s consideration. These materials will undergo public review and comment before the committee’s formal evaluation. The meeting date and agenda for DARTIC’s review will be published on the California Regulatory Notice Register and on OEHHA’s official website once confirmed.
Submissions may be made electronically through OEHHA’s website or mailed directly to their Sacramento office before the deadline.
フィードバック期限
全て scientific information relevant to the reproductive toxicity of p,pʹ-bisphenol chemicals must be submitted by December 1, 2025.
なぜそれが重要なのか
This review could have regulatory implications for manufacturers of plastics, resins, and coatings、 含む 食品包装 producers. If listed under Proposition 65, products containing these chemicals may require reformulation, new labeling, or additional risk communication measures to ensure compliance.
Who This Affects
このアップデートは特に、 規制関連業務, product safety, toxicology、 そして 研究開発チーム within industries that manufacture or utilize bisphenol-based materials. Compliance teams should start evaluating product portfolios for p,pʹ-bisphenol presence and gather supporting scientific evidence.
次のステップ
Organizations are encouraged to:
- Review current formulations for p,pʹ-bisphenols and related compounds.
- Compile relevant toxicological data from internal or published sources.
- Submit supporting evidence to OEHHA before the deadline to contribute to the hazard identification process.
To manage such updates efficiently, leveraging automated intelligence platforms can ensure no deadlines or compliance shifts are missed.
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よくある質問
What is the purpose of OEHHA’s current review of p,pʹ-bisphenol chemicals?
OEHHA is assessing the reproductive toxicity of p,pʹ-bisphenol chemicals to determine whether they should be listed under California’s Proposition 65 as reproductive toxicants.
What type of information is OEHHA requesting for submission?
OEHHA is seeking scientific data such as animal studies, human epidemiological research, そして mechanistic evidence related to reproductive or developmental toxicity.
When and where can public comments be submitted?
Submissions must be sent by December 1, 2025, either electronically via OEHHA’s website or by mail/delivery to its Sacramento office.
How can RegASK help organizations respond to Proposition 65 updates?
RegASKの AI駆動型規制情報プラットフォーム continuously tracks Proposition 65 and other global chemical safety updates, alerting compliance teams in real time and helping them assess impact, manage documentation, and streamline regulatory submissions efficiently.
