California OEHHA Seeks Scientific Data on Reproductive Toxicity of p,p’-Bisphenol Chemicals for Proposition 65 Review

Details of the Review Process

OEHHA will compile and prepare hazard identification materials for DARTIC’s consideration. These materials will undergo public review and comment before the committee’s formal evaluation. The meeting date and agenda for DARTIC’s review will be published on the California Regulatory Notice Register and on OEHHA’s official website once confirmed.

Submissions may be made electronically through OEHHA’s website or mailed directly to their Sacramento office before the deadline.

Feedback Deadline

All scientific information relevant to the reproductive toxicity of p,pʹ-bisphenol chemicals must be submitted by December 1, 2025.

Why It Matters

This review could have regulatory implications for manufacturers of plastics, resins, and coatings, including food packaging producers. If listed under Proposition 65, products containing these chemicals may require reformulation, new labeling, or additional risk communication measures to ensure compliance.

Who This Affects

This update is particularly relevant for regulatory affairs, product safety, toxicology, and R&D teams within industries that manufacture or utilize bisphenol-based materials. Compliance teams should start evaluating product portfolios for p,pʹ-bisphenol presence and gather supporting scientific evidence.

Next Steps

Organizations are encouraged to:

• Review current formulations for p,pʹ-bisphenols and related compounds.
• Compile relevant toxicological data from internal or published sources.
• Submit supporting evidence to OEHHA before the deadline to contribute to the hazard identification process.

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FAQs

What is the purpose of OEHHA’s current review of p,pʹ-bisphenol chemicals?

OEHHA is assessing the reproductive toxicity of p,pʹ-bisphenol chemicals to determine whether they should be listed under California’s Proposition 65 as reproductive toxicants.

What type of information is OEHHA requesting for submission?

OEHHA is seeking scientific data such as animal studies, human epidemiological research, and mechanistic evidence related to reproductive or developmental toxicity.

When and where can public comments be submitted?

Submissions must be sent by December 1, 2025, either electronically via OEHHA’s website or by mail/delivery to its Sacramento office.

How can RegASK help organizations respond to Proposition 65 updates?

RegASK’s AI-driven regulatory intelligence platform continuously tracks Proposition 65 and other global chemical safety updates, alerting compliance teams in real time and helping them assess impact, manage documentation, and streamline regulatory submissions efficiently.